ABDOMINAL ZYGOMYCOTIC - THROMBOANGIITIS IN A PATIENT WITH AML AND T(1-13-14)

The case report of a 61 year-old man with AML M2 FAB, t(1; 13; 14) and zygomycotic mesenterial thromboangiitis is presented. Two induction c ycles of chemotherapy were administered due to primary drug resistance . They were complicated by pneumonia, colonic pseudo-obstruction and p erforation with peritonitis. The patient died on the 40th day of thera py, 4 days after undergoing palliative surgery. Zygomycotic thromboang iitis, which very probably contributed to the intestinal perforation, was confirmed morphologically at necropsy. The novel complex chromosom al translocation t(1; 13; 14) (q31; q32; q24) and the problems connect ed with the diagnosis of invasive fungal infections are discussed.