THE PRESENCE OF CD28-NEGATIVE T-CELLS IN A PATIENT WITH MULTICENTRIC CASTLEMANS-DISEASE

Authors
ISHIYAMA T KOIKE M KAKIMOTO T AKIMOTO Y TSURUOKA N
Citation
T. Ishiyama et al., THE PRESENCE OF CD28-NEGATIVE T-CELLS IN A PATIENT WITH MULTICENTRIC CASTLEMANS-DISEASE, Annals of hematology, 73(4), 1996, pp. 199-200
Citations number
9
Categorie Soggetti
Hematology
Journal title
Annals of hematology → ACNP
ISSN journal
09395555
Volume
73
Issue
4
Year of publication
1996
Pages
199 - 200
Database
ISI
SICI code
0939-5555(1996)73:4<199:TPOCTI>2.0.ZU;2-8
Abstract
We found increased numbers of CD28-negative T cells in a patient with multicentric Castleman's disease (MCD), who also had significantly dec reased interleukin-2 (IL-2) production and impaired T-cell proliferati on. The presence of CD28-negative T cells may be indicative of a funct ional T-cell defect in MCD.