STEREOCONFIGURATION OF ANTEISO-FATTY ACID BIOSYNTHESIZED FROM DL-ISOLEUCINE IN RAT SKIN

Authors
OKU H SAKIHAMA T CHINEN I
Citation
H. Oku et al., STEREOCONFIGURATION OF ANTEISO-FATTY ACID BIOSYNTHESIZED FROM DL-ISOLEUCINE IN RAT SKIN, Bioscience, biotechnology, and biochemistry, 60(10), 1996, pp. 1724-1725
Citations number
8
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
60
Issue
10
Year of publication
1996
Pages
1724 - 1725
Database
ISI
SICI code
0916-8451(1996)60:10<1724:SOAABF>2.0.ZU;2-G
Abstract
Isoleucine (Ile) is a precursor for the biosynthesis of anteiso-fatty acids in rat skin, and among the four possible stereoisomers of Ile, L -Ile, and L-allo-Ile were selectively used for biosynthesis of anteiso -fatty acids, This study examined the optical rotation of anteiso-fatt y acid derived from DL-Ile to ascertain its stereo-configuration, Spec ific rotation of anteiso-fatty acid derived from DL-Ile favorably comp ared with that derived from L-Ile, suggesting the selective biosynthes is of the (S)-enantiomer of anteiso-fatty acid in rat skin.