HIV-INFECTION FROM CRYOPRESERVED BONE ALL OGRAFTS

We reporting four cases of HIV infection caused by bone allografts for m one donor. All transplantations were performed between November 1984 and January 1985. In all, 12 recipients had bone allografts from the HIV-infected donor, 7 of whom are now HIV-negative and 4, HIV-positive . One of the patients died a natural death in her 10th decade. The don or was not been tested before the grafts were harvested, as HIV-antibo dy detection was not possible at the time (October 1984); no HIV-antib ody kits had yet been developed. Subsequent testing of the asservated serum for HIV antibodies gave a positive result. The chronological cou rse of the case is described and the case is discussed in detail.