Jb. Nadol et al., TECHNIQUES FOR HUMAN TEMPORAL BONE REMOVAL - INFORMATION FOR THE SCIENTIFIC COMMUNITY, Otolaryngology and head and neck surgery, 115(4), 1996, pp. 298-305
Human temporal bones provide an irreplaceable resource for study of th
e pathology and pathophysiology of disorders of hearing, balance, tast
e, and facial nerve function. Additional specimens are needed to study
disorders for which there are few human specimens; to increase the nu
mber of specimens for a given disorder to understand the natural varia
bility and expression of the disease entity; to evaluate the accuracy
of otologic diagnoses and the efficacy of otologic treatment modalitie
s; to apply newly available scientific methods, including immunohistoc
hemistry and molecular biologic or molecular genetic techniques; and t
o teach the anatomy of the human ear and modern otologic surgical tech
niques. This article provides information for the scientific community
concerning techniques for temporal bone and auditory brain stem remov
al, including intracranial and extracranial approaches and methods to
minimize postmortem autolysis and cosmetic defects. Close collaboratio
n between physicians and funeral directors will maximize the yield and
utility of these valuable specimens for scientific inquiry and traini
ng.