M. Kotake et al., SHORT STATURE DUE TO GROWTH-HORMONE DEFICIENCY ASSOCIATED WITH CUSHINGS-DISEASE AND ULCERATIVE-COLITIS, Hormone and Metabolic Research, 28(10), 1996, pp. 565-569
We report a rare case of Cushing's disease associated with ulcerative
colitis in a patient primarily treated with growth hormone due to shor
t stature. At the age of fifteen years, the patient had a short statur
e due to GHD and was treated with the extracted GH for a short period
. At the age of twenty-one years, his body weight gradually increased
and, based on the results of several tests, he was diagnosed with Cush
ing's disease and GHD was observed in our patient. The excess secretio
n attenuation of pituitary hormones with reduced secretion periods as
well as the relation between ulcerative colitis and elevated plasma co
rtisol concentrations is briefly discussed in this paper.