IN-VITRO ANTI-MYCOBACTERIUM AVIUM ACTIVITY OF N-(2-HYDROXYETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE AND N-(2-HYDROXYETHYL)-1,2-BENZISOTHIAZOL-3(2H)-THIONE CARBAMIC ESTERS

Authors
PAGANI G BORGNA P PIERSIMONI C NISTA D TERRENI M PREGNOLATO M
Citation
G. Pagani et al., IN-VITRO ANTI-MYCOBACTERIUM AVIUM ACTIVITY OF N-(2-HYDROXYETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE AND N-(2-HYDROXYETHYL)-1,2-BENZISOTHIAZOL-3(2H)-THIONE CARBAMIC ESTERS, Archiv der pharmazie, 329(8-9), 1996, pp. 421-425
Citations number
27
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
329
Issue
8-9
Year of publication
1996
Pages
421 - 425
Database
ISI
SICI code
0365-6233(1996)329:8-9<421:IAAAON>2.0.ZU;2-7
Abstract
A series of N-(2-hydroxyethyl)-1,2-benzisothiazol-3(2H)-one and -thion e carbamic esters have been synthesised and tested against Mycobacteri um avium strains. The MIC values determined by the radiometric broth d ilution method were between 2 and 8 mu g/mL for the benzisothiazolthio ne derivatives and between 16 and 32 mu g/mL or higher for the corresp onding benzisothiazolone derivatives.