SPLENECTOMY IN CASES OF OSTEOMYELOFIBROSI S - INDICATIONS AND RESULTS

Authors
BOHNER H ROTZSCHER VM TIRIER C HEIT W GREINER J
Citation
H. Bohner et al., SPLENECTOMY IN CASES OF OSTEOMYELOFIBROSI S - INDICATIONS AND RESULTS, Chirurg, 67(10), 1996, pp. 1016-1019
Citations number
10
Categorie Soggetti
Surgery
Journal title
Chirurg → ACNP
ISSN journal
00094722
Volume
67
Issue
10
Year of publication
1996
Pages
1016 - 1019
Database
ISI
SICI code
0009-4722(1996)67:10<1016:SICOOS>2.0.ZU;2-C
Abstract
Osteomyelofibrosis is a myeloproliferative disorder in which fibrosis and sclerosis finally lead to bone marrow obliteration. Liver and sple en compensate for bone marrow loss with extramedullary hematopoesis. I n some patients the resulting splenomegaly causes severe symptoms such as local compression, thrombocytopenia and hemolytic anemia, In such patients, splenectomy is the only promising treatment, although it rep resents a significant risk.