In the newborn, severe airway obstruction is a rare occurrence. The po
ssible etiologies include a broad spectrum of diseases with laryngeal
cysts an unusual cause. If diagnosed and properly managed, however, th
e prognosis for this entity is excellent. Three cases presenting with
airway obstruction secondary to unusual laryngeal cysts are the materi
al for this report. In all three, cases the laryngeal cystic structure
extended through the cricothyroid membrane and in two, pathologically
contained both mesodermal and endodermal elements suggesting a laryng
otracheal duplication cyst anomaly, previously unreported. Laryngofiss
ure can be safely employed for complete excision even in the neonatal
period.