DIMORPHIC EXPRESSION OF CALBINDIN-D-28K IN THE MEDIAL BASAL HYPOTHALAMUS FROM PERINATAL MALE AND FEMALE RATS

Authors
LEPHART ED
Citation
Ed. Lephart, DIMORPHIC EXPRESSION OF CALBINDIN-D-28K IN THE MEDIAL BASAL HYPOTHALAMUS FROM PERINATAL MALE AND FEMALE RATS, Developmental brain research, 96(1-2), 1996, pp. 281-284
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
Developmental brain research → ACNP
ISSN journal
01653806
Volume
96
Issue
1-2
Year of publication
1996
Pages
281 - 284
Database
ISI
SICI code
0165-3806(1996)96:1-2<281:DEOCIT>2.0.ZU;2-G
Abstract
Developmental expression of calbindin-D-28K (CALB) in the medial basal hypothalamic (MBH) and amygdaloid (AMY) regions was examined by Weste rn analysis. Males displayed significantly higher CALB levels compared to females in the MBH (but not the AMY) from gestational day 17 throu gh postnatal day 1. These data imply that androgens or other hormonal factors regulate MBH CALB expression which in turn may modulate sexual ly dimorphic brain structures by preventing cell loss during neuronal development.