Cs. Carr et Ma. Edgar, AN UNUSUAL PRESENTATION OF ACUTE LUMBAR NERVE ROOT PAIN - A CASE-REPORT, Spine (Philadelphia, Pa. 1976), 21(20), 1996, pp. 2387-2389
Study Design. This case report illustrates the need to be vigilant of
potential iatrogenic causes of symptoms. A patient with a femoral Hick
man line experienced severe back pain after a chemotherapy infusion co
mmenced and developed a right quadriceps weakness and absent knee jerk
. Objectives. To highlight the severe side effects possible with the u
se of Hickman lines and chemotherapy. Summary of Background Data. Ther
e are numerous causes of lumbar radicular pain, and these can coexist
in the same patient. This patient had a known malignant process involv
ing the retroperitoneum, but the actual cause of the severe pain relat
ed to the management of the malignancy rather than the malignancy itse
lf. There are no reported cases of such a complication from a Hickman
line. Methods. This patient was admitted to hospital for investigation
and treatment of severe back pain after the start of a continuous inf
usion of chemotherapy for ail inoperable cholangiocarcinoma. The patie
nt went on to develop a right quadriceps weakness before the investiga
tions could reveal the cause of the problem. Results. The pain and wea
kness resolved after cessation of the infusion and removal of the Hick
man line. Conclusions. The principles-of clinical medicine involve car
eful history taking and examination and considering all the differenti
al diagnoses fully. Also, the possibility of multiple pathology and ia
trogenic causes should be assessed. This patient was receiving palliat
ive treatment: only, and this unfortunately led to additional disabili
ty, which may have been avoidable or less severe.