CONVERSION DEPENDENCE OF ENANTIOSELECTIVE HYDROGENATION OF (E)-ALPHA-PHENYLCINNAMIC ACID ON CINCHONIDINE-MODIFIED PD TIO2 CATALYST/

Authors
NITTA Y KOBIRO K
Citation
Y. Nitta et K. Kobiro, CONVERSION DEPENDENCE OF ENANTIOSELECTIVE HYDROGENATION OF (E)-ALPHA-PHENYLCINNAMIC ACID ON CINCHONIDINE-MODIFIED PD TIO2 CATALYST/, Chemistry Letters, (10), 1996, pp. 897-898
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
10
Year of publication
1996
Pages
897 - 898
Database
ISI
SICI code
0366-7022(1996):10<897:CDOEHO>2.0.ZU;2-N
Abstract
The enantioselectivity of a cinchonidine-modified Pd/TiO2 catalyst var ied with the extent of conversion in the hydrogenation of (E)-alpha-ph enylcinnamic acid. The incremental enantioselectivity reached a maximu m at an early stage of the reaction. Under optimized reaction conditio ns, optical yields of up to 72%e.e. of (S)-(+)-2,3-diphenylpropionic a cid were obtained at 100% conversion.