NEW THERAPEUTIC AVENUES IN AUTOIMMUNITY

During the last decade, much progress has been made in the understandi ng of processes that lead to autoimmunity. Cellular interactions media ted through cytokines and adhesion molecules were found to play a majo r role in the genesis of autoimmune conditions, During this period, we learned to recruit monoclonal antibodies to manipulate these delicate processes and to divert their outcome to a path we control better. Ou r comprehension of IVIG (intravenous immunoglobulin therapy) has broad ened, and new indications for the implementation of this promising the rapy have been pursued. In this review, we shed light on new therapeut ic modalities that have been published since our previous report and d iscuss new data concerning the old modalities.