PURPOSE: To evaluate the usefulness of computed tomography (CT) in the
diagnosis of mediastinitis following median sternotomy. MATERIALS AND
METHODS: Fifty patients aged 6 weeks to 80 years (31 male, 19 female)
who underwent CT for clinically suspected mediastinitis following med
ian sternotomy were retrospectively identified. CT scans were evaluate
d for primary findings (localized mediastinal fluid, pneumomediastinum
, or both) versus secondary or other findings (mediastinal edema, aden
opathy, pleural effusion, or a sternal or lung abnormality). Patients
were divided into three groups on the basis of the CT findings and fin
al clinical diagnosis: those with primary CT signs and a final diagnos
is of mediastinitis, those with primary CT signs of mediastinitis and
a different final diagnosis, and those with neither primary CT finding
s nor a final diagnosis of mediastinitis. RESULTS: All patients with c
linical mediastinitis had primary CT findings. These patients underwen
t CT an average of 24 days after surgery. Patients with primary CT fin
dings and a final clinical diagnosis of something other than mediastin
itis underwent CT an average of 9 days following surgery. Through post
operative day 14, CT had a sensitivity of 100% for clinical mediastini
tis but a specificity of 33%; after postoperative day 14, the sensitiv
ity was 100% and the specificity was 100%. CONCLUSION: Primary CT find
ings are not specific for mediastinitis through postoperative day 14;
after day 14, they are highly indicative of mediastinitis.