Eb. Fowler et al., PYOGENIC GRANULOMA ASSOCIATED WITH GUIDED TISSUE REGENERATION - A CASE-REPORT, Journal of periodontology, 67(10), 1996, pp. 1011-1015
A pyogenic granuloma is an exuberant growth of granulation tissue seco
ndary to irritation. intraorally, it can present with a wide array of
clinical appearances, ranging from a sessile lesion to an elevated mas
s. Pyogenic granulomas generally are soft, painless, and deep red to r
eddish-purple in color. They are usually 0.5 to 1.0 cm in diameter, mo
re common in females, and often found on the keratinized tissue. This
case is interesting because the pyogenic granuloma was found associate
d with guided tissue regeneration and the lingual alveolar mucosa. The
lesion arose after demineralized freeze dried bone allograft and an e
xpanded polytetrafluoroethylene (ePTFE) membrane were utilized to repa
ir osseous defects. Five weeks after surgery, the patient presented fo
r routine follow-up where suppuration associated with the membrane was
noted along with an exophytic growth of the lingual alveolar mucosa.
The ePTFE membrane was removed alone with an excisional biopsy of one
of the growths. By 10 days after the removal of ePTFE, the lesion spon
taneously healed. Histologic evaluation of the tissue was consistent w
ith a pyogenic granuloma. This is the first case in the literature of
a pyogenic granuloma associated with a routine guided tissue regenerat
ive surgery using a non-resorbable membrane and allograft.