Cg. Last et al., A PROSPECTIVE-STUDY OF CHILDHOOD ANXIETY DISORDERS, Journal of the American Academy of Child and Adolescent Psychiatry, 35(11), 1996, pp. 1502-1510
Objective: To evaluate course and outcome of DSM-III-R anxiety disorde
rs prospectively in clinically referred children. Method: Children wer
e blindly and repeatedly assessed with a structured diagnostic intervi
ew over a 3- to 4-year period to determine recovery from anxiety disor
der and development of new psychiatric disorders. Both psychopathologi
cal (attention-deficit hyperactivity disorder, n = 50) and never psych
iatrically ill (NPI, n = 83) controls served as comparison groups for
children with anxiety disorders (n = 84). Results: The majority of chi
ldren (82%) were free from their intake anxiety disorders by the end o
f the follow-up. Relapse of these anxiety disorders after remission wa
s rare (8%). During follow-up, anxious children were more likely to de
velop new psychiatric disorders (30%), primarily new anxiety disorders
(16%), than were NPI children (11% and 2%, respectively), but not psy
chopathological controls (42% and 10%, respectively). Conclusions: Ove
rall, results suggest a favorable outcome with respect to diagnostic s
tatus for clinically referred children with anxiety disorders. However
, these children may be at risk for new psychiatric disorders over tim
e.