1,3-ASYMMETRIC INDUCTION IN ENOLATE ALKYLATION REACTIONS OF N-PROTECTED GAMMA-AMINO ACID-DERIVATIVES

Authors
HANESSIAN S SCHAUM R
Citation
S. Hanessian et R. Schaum, 1,3-ASYMMETRIC INDUCTION IN ENOLATE ALKYLATION REACTIONS OF N-PROTECTED GAMMA-AMINO ACID-DERIVATIVES, Tetrahedron letters, 38(2), 1997, pp. 163-166
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
2
Year of publication
1997
Pages
163 - 166
Database
ISI
SICI code
0040-4039(1997)38:2<163:1IIEAR>2.0.ZU;2-M
Abstract
Dianions derived from N-TFA and N-Boc gamma-amino acid esters and amid es undergo highly stereoselective alpha-alkylation reactions The roles of HMPA, of the cation, the electrophile, and of steric factors were studied. Copyright (C) 1996 Elsevier Science Ltd