SYNTHESIS OF A NOVEL ALPHA-GLUCOSIDE OF THE POWERFUL GLUCOSIDASE INHIBITOR 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL VIA ENZYMATIC GLUCOSYLATION OF 5-AZIDO-5-DEOXY-D-FRUCTOPYRANOSE

Citation
K. Dax et al., SYNTHESIS OF A NOVEL ALPHA-GLUCOSIDE OF THE POWERFUL GLUCOSIDASE INHIBITOR 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL VIA ENZYMATIC GLUCOSYLATION OF 5-AZIDO-5-DEOXY-D-FRUCTOPYRANOSE, Tetrahedron letters, 38(2), 1997, pp. 225-226
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
38
Issue
2
Year of publication
1997
Pages
225 - 226
Database
ISI
SICI code
0040-4039(1997)38:2<225:SOANAO>2.0.ZU;2-D
Abstract
Regio- and stereoselective enzymatic glucosylation of 5-azido-5-deoxy- D-fructopyranose with the aid of commerically available alpha-glucosid ase from yeast allows easy access to the corresponding 4-O-alpha-D-glu copyranosyl derivative of this non-natural ketose. This disaccharide g ives, in one step, access to y-3-O-alpha-D-glucopyranosyl-2,5-imino-D- mannitol. Copyright (C) 1996 Elsevier Science Ltd