T. Okada et al., ULTRA-LOW-FIELD MAGNETIC-RESONANCE-IMAGING IN UPPER AIRWAYS OBSTRUCTION IN SLEEP-APNEA SYNDROME, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 50(5), 1996, pp. 285-289
The hypothesis that the sites of upper airways obstruction (UAO) are v
aried in a patient with obstructive sleep apnea syndrome (OSAS) among
different sleep stages is studied. Four patients with OSAS underwent u
ltra-low-field magnetic resonance imaging (MRI) with a field strength
of 0.064 Tesla provided real-time images and generated less noise and
necessitated less strict magnetic isolation compared with conventional
high-field MRI. After the fixed end-apneic sleep stage was determined
, the polysomnogram was switched off and ultra-low-field MRI was comme
nced. The effects of continuous positive airway pressure (CPAP) on the
upper airway patency in the deepest sleep stage obtained for each pat
ient was assessed. Upper airway obstruction was found at the level of
the palatopharynx (PP) at sleep onset extended to the glossopharynx (G
P) during rapid eye movement (REM) sleep in two cases and during NREM
sleep in one case. This combined PP and GP obstruction was observed fr
om sleep onset and remained unchanged in one case. The patent upper ai
rways were observed during treatment with CPAP during REM sleep in two
patients and during stage two of NREM sleep in the other two patients
. It can be concluded that the sites of UAO vary in a patient with OSA
S in different sleep stages. The results also suggest the use of the u
ltra-low-field MRI in order to visualize the dynamic and real-time beh
aviors of the upper airways during sleep in patients with OSAS.