Background. Recently laparoscopy has been described as an alternative
approach for performing adrenalectomy. This study attempts to define t
he frequency and indications for the various approaches to adrenalecto
my including laparoscopy. Methods. From October 1992 to December 1995,
43 adrenal glands were excised from 40 patients, of whom 23 were wome
n and 17 were men. Their ages ranged from 16 to 71 years. Nineteen ope
rations were performed for pheochromocytoma, 10 for cortical adenoma (
CAd), 6 for aldosteronoma, 4 for adrenocortical cancer (ACC), 1 for Cu
shing's disease (CD), and 1 for hemorrhagic cyst. Adrenalectomy was ac
complished via a laparoscopic operation in 20 patients (8 CAds, 6 pheo
chromocytomas, 5 aldosteronomas, and 1 HC) and via an open operation i
n 19 patients (11 pheochromocytomas, 4 ACCs, 2 CAds, 1 CD, and 1 aldos
teronoma). One patient with bilateral pheochromocytoma had an open and
a laparoscopic adrenalectomy. Results. Open operations included 15 tr
ansabdominal, 4 posterior, and 3 thoracoabdominal approaches for 22 gl
ands. Laparoscopic operations included 17 transabdominal and 4 retrope
ritoneal approaches for 21 glands. Reasons for open operations include
d obesity (1), patient choice (2), failed laparoscopy (2), previous ab
dominal surgery (3), extraadrenal location (5); and gland size greater
than 8 cm (9). Of these cases, the two patient, choices, the two fail
ed laparoscopies, and two of the three previous abdominal operations w
ere appropriate for laparoscopy. Each of the posterior approaches coul
d have been done laparoscopically. Conclusions. More than 60% of surgi
cally treatable adrenal disease may be approached laparoscopically. Tr
ansabdominal, and on occasion, thoracoabdominal approaches are indicat
ed for larger adrenal lesions. Surgeons operating on the adrenal gland
should be familiar with each of these various approaches for adrenale
ctomy.