GROWTH OF CHLAMYDIA-PNEUMONIAE INDUCES CYTOKINE PRODUCTION AND EXPRESSION OF CD14 IN A HUMAN MONOCYTIC CELL-LINE

Authors
HEINEMANN M SUSA M SIMNACHER U MARRE R ESSIG A
Citation
M. Heinemann et al., GROWTH OF CHLAMYDIA-PNEUMONIAE INDUCES CYTOKINE PRODUCTION AND EXPRESSION OF CD14 IN A HUMAN MONOCYTIC CELL-LINE, Infection and immunity, 64(11), 1996, pp. 4872-4875
Citations number
25
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
11
Year of publication
1996
Pages
4872 - 4875
Database
ISI
SICI code
0019-9567(1996)64:11<4872:GOCICP>2.0.ZU;2-K
Abstract
Chlamydia pneumoniae was able to survive and to multiply in the human monocytic cell line Mono Mac 6, Growth of C. pneumoniae induced produc tion of tumor necrosis factor alpha, interleukin 1 beta, and interleuk in 6, as well as up-regulation of the CD14 molecule in a time-dependen t manner, Infection of monocytic cells and a proinflammatory cytokine response may be important in C. pneumoniae pathogenesis.