A SMALL-VOLUME SPACER FOR USE WITH A BREATH-OPERATED PRESSURIZED METERED-DOSE INHALER

Authors
HARDY JG JASUJA AK FRIER M PERKINS AC
Citation
Jg. Hardy et al., A SMALL-VOLUME SPACER FOR USE WITH A BREATH-OPERATED PRESSURIZED METERED-DOSE INHALER, International journal of pharmaceutics, 142(1), 1996, pp. 129-133
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
International journal of pharmaceutics → ACNP
ISSN journal
03785173
Volume
142
Issue
1
Year of publication
1996
Pages
129 - 133
Database
ISI
SICI code
0378-5173(1996)142:1<129:ASSFUW>2.0.ZU;2-B
Abstract
A small volume spacer, the Optimiser, has been evaluated for use with the Easi-Breathe breath-operated inhaler. Oropharyngeal deposition in healthy subjects was reduced by 80% by the use of the spacer. The Opti miser spacer removes most of the non-respirable drug, without compromi sing the fine particle dose delivered from the Easi-Breathe inhaler.