Acromegaly is an uncommon disease due to excessive amounts of growth h
ormone. Benign and malignant tumors have been reported in acromegalic
patients. A 41-year-old female patient who had been followed up becaus
e of acromegaly by the endocrinology department for two years, was adm
itted to the hematology department for the evaluation of pancytopenia
and the related signs and symptoms. Dopamine agonists were being used
till a diagnosis of 'acute promyelocytic leukemia' was made. Occurrenc
e of 'acute promyelocytic leukemia' in the course of acromegaly may ha
ve been caused by excessive endogenous GH or may be a coincidental sit
uation.