Twenty-eight patients affected by non-resectable pelvic recurrence of
a primary pelvic malignant neoplasm were treated by isolated pelvic pe
rfusion, at mean hyperthermia, with different drugs, chosen taking int
o account tumor chemosensitivity. All patients had been previously tre
ated. Four complete and six partial responses were observed; nine pati
ents had stable disease and four other patients were non-responders an
d died due to progression in a few months. Two patients were lost to f
ollow-up, one patients died for other reasons and two recent patients
are not yet assessable.