To clarify the factors affecting survival of the patients with differe
ntiated thyroid cancer and pulmonary metastases, 46 patients treated a
t our hospital during the past 23 years were studied using statistical
analysis. Nineteen patients died as a result of their thyroid cancer.
The follow-up period ranged from 1 to 31 years with a median of 10.5
years. Age at primary surgery, interval between primary surgery and ap
pearance of pulmonary metastases and RI therapy affected survival from
primary surgery and age at pulmonary metastases and RI therapy determ
ined survival after pulmonary metastases, as revealed by the Cox propo
rtional hazard model. These results suggest that prognostic factor of
patients with differentiated thyroid cancer and pulmonary metastases i
s the age at initial surgery and at appearance of pulmonary metastases
. But RI therapy could change the course of pulmonary metastases of th
yroid cancer.