T. Nagakawa et al., ASSESSMENT OF POSTOPERATIVE DIGESTIVE FUNCTION AFTER PANCREATICO-DUODENECTOMY - A COMPARISON OF RECONSTRUCTION TECHNIQUES, Hepato-gastroenterology, 43(11), 1996, pp. 1218-1224
Background/Aims: Malabsorption is a frequent complication following pa
ncreatico-duodenectomy (PD) for pancreatic carcinoma. Gastrojejunostom
y followed by Billroth I type of reconstruction (PD III) has been adva
nced to prevent this disorder. We compared postoperative digestion and
absorption determined by I-131-triolein, D-xylose and pancreatic func
tion diagnostant (PFD) after extensive PD followed by one of two recon
structive procedures. Material and Methods: Postoperative digestive an
d absorptive functions in patients operated by Child's method (PD II)
were compared with patients in whom the stomach emptied proximal to th
e pancreas and bile duct (PD III). Results: The absorption of D-xylose
was significantly higher (1.24+/-0.36 g vs. 0.72+/-0.21 g) in the PD
III group. No difference was noted in pancreatic endocrine secretion b
etween the two groups. Biliary scintigraphy revealed increased bile se
cretion. in She PD III group. Conclusions: These results suggest that
PD III is superior to PD II following extensive PD.