Mn. Kulaylat et al., MULTIMODALITY TREATMENT OF SQUAMOUS-CELL CARCINOMA COMPLICATING PILONIDAL DISEASE, The American surgeon, 62(11), 1996, pp. 922-929
Malignant degeneration is an unusual complication of chronic primary o
r recurrent pilonidal disease. To date, only 43 cases have been report
ed, the great majority being squamous cell type, Historically, these c
ases were treated with primary excision. Recurrence following such tre
atment was high and prognosis poor compared with nonmelanoma skin canc
er. We describe a patient with squamous cell carcinoma arising in chro
nic pilonidal disease, who is disease-free 3 years after adjuvant radi
ation therapy following radical excision. This communication describes
the clinicopathologic features of 38 cases of squamous cell carcinoma
arising in pilonidal disease and suggests treatment modalities.