Purpose: The PIOPED criteria in their original and revised forms are t
oday's standards in the interpretation of ventilation-perfusion scinti
graphy. When the PIOPED criteria are used by experienced raters with t
raining in consensus interpretation, the agreement rates have been dem
onstrated to be excellent. Our purpose was to investigate the rates of
agreement between 2 experienced raters from different hospitals who h
ad no training in consensus interpretation. Material and Methods: The
2 raters investigated a population of 195 patients. This group include
d 72 patients from a previous study who had an intermediate probabilit
y of pulmonary embolism and who had also been examined by pulmonary an
giography. Results: The results demonstrated moderate agreement rates
with a kappa value of 0.54 (0.45-0.63 in a 95% confidence interval), w
hich is similar to the kappa value of the PIOPED study but significant
ly lower than the kappa values of agreement rates among consensus-trai
ned raters. There was a low consistency in the intermediate probabilit
y category, with a proportional agreement rate of 0.39 between the exp
erienced raters. Conclusion: The moderate agreement rates between rate
rs from different hospitals make it difficult to compare study populat
ions of a certain scintigraphic category in different hospitals. Furth
er investigations are mandatory for accurate diagnosis when the scinti
grams are in the category of intermediate probability of pulmonary emb
olism.