THE SWEDISH NEUROSURGICAL school was created during the 1920s by Herbe
rt Olivecrona, who became the first professor of neurosurgery at the K
arolinska Institute. He pioneered procedures for the treatment of arte
riovenous malformations and acoustic neuromas. He was among the first
to make direct attacks on berry aneurysms. Many outstanding neurosurge
ons in Europe were trained by him. Clinical research to refine and min
imize surgical interventions has continued to be the most important fe
ature of the neurosurgery department at the Karolinska Institute. Lars
Leksell, Olivecrona's successor, was a leader in stereotactic surgery
and the creator of radiosurgery. His tool, the gamma knife, is in wor
ldwide use today. Leksell and his students have defined the indication
s for radiosurgery and introduced stereotactic techniques into microsu
rgery. Today, 3000 neurosurgical procedures are performed annually in
the four operating rooms of the department of neurosurgery. More than
300 of the procedures are performed with the gamma knife, and at least
one-third of the patients are foreign referrals. There is a strong em
phasis on clinically oriented research and development. There are rese
arch programs for radiosurgery, management of pain, neurooncology, tre
atment of traumatic brain injury, and treatment of vasospasm after sub
arachnoid hemorrhage.