Sf. John et al., THE COMBINED EFFECTS OF PLASMA AND HYDROGEL COATING ON ADHESION OF STAPHYLOCOCCUS-EPIDERMIDIS AND STAPHYLOCOCCUS-AUREUS TO POLYURETHANE CATHETERS, FEMS microbiology letters, 144(2-3), 1996, pp. 241-247
The adhesion of three Staphylococcus epidermidis and three S. aureus c
linical isolates, to uncoated and hydrogel-coated polyurethane cathete
rs was tested, following pretreatment of catheters with human plasma,
Plasma significantly decreased the adhesion of S. epidermidis strains
to uncoated polyurethane catheters, but had no significant effect on t
he adhesion to hydrogel-coated catheters. The influence of plasma on a
dhesion of S. aureus strains to catheters was strain dependent. Plasma
significantly increased the adhesion of one strain (SA6) to uncoated
catheters, For two other strains (SA3 and SA14) plasma produced no cle
ar effect on their adhesion to uncoated catheters; adhesion values for
each strain showed either a small but significant increase or a repli
cate-dependent increase or decrease, However, plasma significantly inc
reased the adhesion of all S. aureus strains to hydrogel-coated polyur
ethane catheters. Overall, with the exception of one batch culture of
S. epidermidis strain SE3 tested, attachment to plasma-treated hydroge
l-coated catheters was statistically significantly lower, by up to 85%
, than attachment to plasma-treated uncoated catheters for both S. epi
dermidis and S. aureus.