O. Jourdain et al., ENDOMETRIAL ND-YAG LASER-ABLATION BY HYSTEROFIBROSCOPY - LONG-TERM RESULTS OF 137 CASES, European journal of obstetrics, gynecology, and reproductive biology, 69(2), 1996, pp. 103-107
Objective: In our gynecology department, we have been performing endom
etrial laser ablation (ELA) under video control using a flexible hyste
roscope since 1989. The aim of this study is to evaluate the long term
results of our experience. Study, design: We went back to the files o
f 137 patients treated between 1989 and 1993. These women (mean age 42
years) exhibited menorrhagia unamenable to medical treatments which h
ad been developing for 28 months. Mean hysterometry was 9.8 cm. A hyst
eroscopy with ELA was performed. Our procedure lasts 19 min on average
and uses 0.9 1 of glycocol. There were no perforations. Six patients
presented a fever above 38 degrees C within the next 48 h; only one de
veloped a true endometritis necessitating antibiotherapy. One patient
who had received several GnRH agonist courses had a coagulation of the
uterus and had to be hysterectomised. Results: Nine patients were los
t to follow-up; for the others, mean follow-up was 32 months. Seventee
n women (13.3%) were hysterectomised, including the patient with a coa
gulation necrosis of the myometrium. In most cases, this was for undet
ected adenomyosis or fibromas evolving after hysteroscopy. Bleeding re
curred in two other patients; they refused hysterectomy but should be
counted as failures of this method. Among the 109 patients (85.1%) con
sidered a success, 35 have had menopause since the procedure. Conclusi
on: ELA is a simple quick procedure which significantly reduces the nu
mber of hysterectomies. In addition, the economic value of ELA is begi
nning to be assessed in the literature. This long-term study should al
low the indications to be better defined by eliminating patients with
a high risk of failure and should lead to improved results.