Mg. Giusachiferi et al., TRANSVAGINAL ULTRASOUND, UTERINE BIOPSY AND HYSTEROSCOPY FOR POSTMENOPAUSAL BLEEDING, International journal of gynaecology and obstetrics, 55(1), 1996, pp. 39-44
Objectives: To determine the importance of endometrial biopsy and tran
svaginal ultrasound in patients with postmenopausal bleeding. Methods:
Eighty patients with postmenopausal bleeding were submitted to transv
aginal ultrasound followed by endometrial biopsy. Hysteroscopy and dil
atation and curettage were carried out to confirm normality of the ute
rine cavity. Results: The endometrial echo could be visualized in all
patients with postmenopausal bleeding. The biopsy failed to detect one
case (1.38%) of adenocarcinoma and 14 cases (17.5%) of endometrial po
lyps. The sensitivity in detecting endometrial malignancy was 94.44% f
or endometrial biopsy and 100% for transvaginal ultrasound, when the e
ndometrial thickness was more than 8 mm. Conclusions: When the thickne
ss of the endometrial echo is less than 3 mm there is no need for anat
omopathologic investigation. When this limit was adopted, all cases we
re associated with endometrial atrophy, and when the limit was 4 mm or
more, active endometria were detected, requiring further histopatholo
gic investigation by hysteroscopy and directed biopsies. Above 8 mm, m
alignancy may be found.