Objective: The clinical characteristics of ovarian tumors associated w
ith pregnancy were investigated. Method: A series of 106 cases of ovar
ian tumor surgically resected during pregnancy was investigated with r
espect to incidence, clinicopathologic features and outcome. Results:
Among 106 cases undergoing ovarian surgery, 31 (29.2%), 70 (66%) and f
ive (4.7%) were diagnosed as physiologic, benign and malignant, respec
tively. The incidence of benign neoplastic tumor was 1:112 deliveries
and that of malignant neoplastic tumor was 1:1684 deliveries. Dermoid
cyst was the most common lesion found. Of the 70 benign tumors, 51 (72
.9%) were greater than 8 cm in diameter and 55 (78.6%) were preoperati
vely diagnosed before the 10th gestational week; 44 (62.9%) were opera
ted before the 15th gestational week. The spontaneous abortion rate in
80 cases followed up after surgery was only 10%, 61 patients (76.3%)
progressing to full-term delivery. Five malignant tumors included thre
e epithelial carcinomas, one embryonal carcinoma and one dysgerminoma.
Conclusion: Ovarian surgery in the first trimester for persistent or
enlarging masses is important to obtain a final histologic diagnosis a
nd rule out malignancy.