Spigelian hernias are spontaneous lateral ventral abdominal wall herni
as occurring along the subumbilical portion of the semilunar line of S
pigel and through the spigelian fascia. It is an uncommon hernia with
a variety of presentations that usually remains undiagnosed until expl
oratory laparotomy. We report a 62-year-old woman with an elevated CA-
125 value of 149 and intraoperative findings of a left spigelian herni
a. A simple herniorrhaphy was performed, and she is without evidence o
f recurrence of the hernia after 9 months of follow-up. The CA-125 val
ue returned to normal levels. Spigelian hernias are rarely suspected b
ut, when encountered, should be repaired. A review of the anatomic fea
tures and management of this unusual defect is given.