ENZYMATIC-REACTIONS IN LIPOSOMES

A survey of literature reports, concerning the activity of water-solub le enzymes entrapped inside liposomes, demonstrates the general feasib ility of liposomes as enzyme-containing submicrometer-sized reactors. Although systematic studies are missing, the investigation of the cata lytic properties of enzyme-containing liposomes is generally restricte d to systems with small, uncharged substrates for which the lipid bila yer of the liposomes is permeable. So far, only a few attempts have be en undertaken to decrease this permeability barrier.