PEDIATRIC HEPATOBILIARY DISEASE

Recent advances in pediatric hepatobiliary disease are reflected by ch anges in three areas. New outcome data, therapeutic advances, developm ent of hepatocellular carcinoma, and genetic mapping on syndromic pauc ity of intralobular bile ducts (Alagille syndrome) are reviewed. Bilia ry atresia outcome data, ideas regarding screening policy, and the rol e of reovirus in its pathogenesis are addressed, Finally, sclerosing c holangitis, its clinical picture in the pediatric population, and diag nostic techniques, including pediatric endoscopic retrograde cholangio pathy, are reviewed.