Z. Rihmer et al., ANTIDEPRESSANT-INDUCED HYPOMANIA IN OBSESSIVE-COMPULSIVE DISORDER, International clinical psychopharmacology, 11(3), 1996, pp. 203-205
Out of ten consecutive patients with DSM-III-R obsessive-compulsive di
sorder without any previous history of bipolarity, three patients show
ed antidepressant-induced hypomania (clomipramine, one patient; fluvox
amine, two patients) within the first 5 to 8 weeks of the drug treatme
nt. These data support the previous results on a strong association be
tween obsessive-compulsive disorder and bipolar affective illness.