D. Tousoulis et al., VON-WILLEBRAND-FACTOR IN PATIENTS EVOLVING Q-WAVE VERSUS NON-Q-WAVE ACUTE MYOCARDIAL-INFARCTION, International journal of cardiology, 56(3), 1996, pp. 259-262
We assessed the changes in plasma von Willebrand factor level concentr
ation in 10 patients with Q-myocardial infarction and in six patients
with non-Q-myocardial infarction who did not receive thrombolytic trea
tment. Concentrations of von Willebrand factor antigen were measured b
y an enzyme linked immunoassay method in plasma samples obtained twice
daily for 4 consecutive days. In patients with Q-wave myocardial infa
rction, a significant rise in von Willebrand factor antigen levels (P<
0.05) occurred after admission and persisted for 3 days. No significan
t changes were found in plasma concentration of fibrinogen. In conclus
ion, von Willebrand factor antigen levels were greater in patients wit
h Q-wave compared to patients with non-Q-wave myocardial infarction.