SUBCUTANEOUSLY IMPLANTED TUMOR - AN HYPOTHESIZED NOVEL-APPROACH TO INDIVIDUALIZED IMMUNOTHERAPY FOR LUNG-CARCINOMA

A novel approach to immunotherapy for the treatment of lung carcinoma is hypothesized. If a lung tumour removed at operation is implanted su bcutaneously within a Millipore chamber in that patient, then a local immune response may be induced. It is suggested that this subcutaneous ly induced immune response could improve the prognosis of the underlyi ng tumour either of its own accord or by its use as an adoptive immuno therapy. Spread of the tumour locally would be prevented by containmen t within the Millipore chamber. The hypothesis has been supported by e xperimental observations from a pilot study.