We report the case of a young woman with refractory thrombotic thrombo
cytopenic purpura (TTP), treated with different therapies (standard th
erapy with plasma exchange, prostacyclin infusion, vincristine sulfate
) and responding to these for brief periods. High-dose immunoglobulin
(400 mg/kg/day for 5 days), on the other hand, yielded a complete resp
onse which has lasted for 14 months up to the time of this report.