T. Heitmann et al., A KINETIC-MODEL OF GROWTH AND PRODUCT FORMATION OF THE ANAEROBIC MICROORGANISM THERMOANAEROBACTER-THERMOHYDROSULFURICUS, Journal of biotechnology, 50(2-3), 1996, pp. 213-223
A model is developed to describe the growth, product formation and enz
yme synthesis of the microorganism Thermoanaerobacter thermohydrosulfu
ricus. It differentiates between extracellular enzymatic starch degrad
ation and the microorganism's constant specific growth rate, combined
with the ingestion of maltose and maltotriose (the products of starch
cleavage). The formation of growth dependent products like ethanol, ac
etate and the synthesis of the cell-associated enzyme, amylopullulanas
e, are formulated with constant yield coefficients. In contrast, both
the non-growth dependent product lactate, and extracellular enzyme act
ivity are linked to an intracellular substrate concentration. Most of
the parameters used in the model are evaluated from batch culture or l
iterature. The calculated results are compared with experimental data.