In the Oleaceae family, the most allergenic pollen is produced by Olea
europaea, the olive tree, which in the Mediterranean area has been re
cognized as one of the most important cause of seasonal respiratory al
lergy. The olive pollination season lasts from May to the end of June
and sometimes causes severe symptoms (oculorhinitis and/or bronchial a
sthma). Olive pollinosis is quite rare in the form of monosensitizatio
n. Although adults are affected the most, olive sensitization can be r
ecognized in children, too. However, it is not easy to be sure about t
he clinical relevance of allergic sensitization to olive, even in pati
ents with positivity to this pollen, as results from allergological te
sts in vivo and/or in vitro, because positivity to Olea pollen is not
equivalent to clinical responsibility, above all in patients without s
easonal respiratory symptomatology. Studies on the allergenic content
of O. europaea pollen are currently in progress. In Northern and Centr
al Europe, where there are no olive trees, there are two commonly occu
rring genera of the Oleaceae family, namely Fraxinus and Ligustrum, bu
t these have a low frequency of allergic sensitization. A fourth anemo
philous member of the Oleaceae, Phillyrea, has a more regional distrib
ution in some parts of the Mediterranean. Other nonanemophilous and us
ually not allergenic Oleaceae genera are Forsythia, Jasminum and Syrin
ga.