Rj. Leo et al., UTILITY OF THYROID-FUNCTION SCREENING IN ADOLESCENT PSYCHIATRIC-INPATIENTS, Journal of the American Academy of Child and Adolescent Psychiatry, 36(1), 1997, pp. 103-111
Objective: Thyroid function abnormalities have been associated with ps
ychiatric symptoms. This study examines the utility of thyroid screeni
ng among adolescent psychiatric inpatients. Method: A retrospective ch
art review of 196 first-time admissions to an adolescent psychiatric u
nit was conducted. Charts were screened for demographics, presence/abs
ence of thyroid function testing, history of thyroid disease, medicati
on/illicit substance use, and other factors of influence on thyroid te
sting. Thyroid test results were reviewed for abnormalities. Results:
Thyroid function testing was conducted in 150 of the 196 admissions. F
ifty-two patients had abnormalities, most of which were isolated abnor
malities of thyroxine (T4) or triiodothyronine uptake (T3U). Laborator
y diagnosis of hyperthyroidism and mild hypothyroidism was met by two
and eight patients, respectively; five had profiles that were normal u
pon subsequent testing 1 week later. None of the patients was symptoma
tic, and none required thyroid supplementation or antithyroid medicati
ons. Gender differences in T4 and T3U were noted, and age was positive
ly correlated with T3U. Conclusions: Thyroid function tests may be spu
riously abnormal in routine screening of newly admitted psychiatric pa
tients. Routine thyroid screening among adolescent psychiatric inpatie
nts is unwarranted except in patients who display physical signs or sy
mptoms suggestive of thyroid disease.