Two Bolivian Aspidosperma species were investigated. The seed and stem
bark of Aspidosperma macrocarpon Mart. contain six known alkaloids: (
-)-vincadifformine, ervinceine, kopsanone, kopsinine, kopsanol in the
seed, and kopsanone, kopsinine, kopsanol, 18-epikopsanol in the stem b
ark. The stem bark of Aspidosperma pyrifolium Mart. contains eleven kn
own alkaloids: (-)-vincadifformine, O-demethylpalosine, halocine, N-fo
rmylaspidospermidine, vallesine, demethoxyaspidospermine, palosine, (-
)-aspidospermine, aspidospermidine, akuammicine, tubotaiwine, beside t
he two new bases dehydroxyhaplocidine and 10-methoxyaspidospermidine.