INFLUENCE OF 3 MEMBRANE TYPES ON HEALING OF BONE DEFECTS

Citation
Tb. Crump et al., INFLUENCE OF 3 MEMBRANE TYPES ON HEALING OF BONE DEFECTS, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 82(4), 1996, pp. 365-374
Citations number
44
Categorie Soggetti
Pathology,Surgery,"Dentistry,Oral Surgery & Medicine
ISSN journal
10792104
Volume
82
Issue
4
Year of publication
1996
Pages
365 - 374
Database
ISI
SICI code
1079-2104(1996)82:4<365:IO3MTO>2.0.ZU;2-I
Abstract
Objectives. To determine and compare osseous regeneration associated w ith three guided tissue regeneration membrane types (expanded polytetr afluoroethylene, dense polytetrafluoroethylene, and an absorbable poly lactic acid/citric acid ester base) and removal forces required for ex panded and dense polytetrafluoroethylene membranes. Study design, Bila teral osseous defects were created in 30 adult rat calvaria; one defec t was covered with a lest membrane and the other received no membrane (control). After 2 or 4 weeks, forces required for membrane removal fr om the tissues were electronically determined, and the calvaria remove d and decalcified. Sections through the defects were stained and evalu ated electronically and microscopically. Data were analyzed statistica lly. Results. Microscopic evaluation with Mann-Whitney U test revealed that dense polytetrafluoroethylene was associated with significantly greater bone formation than expanded polytetrafluoroethylene (p = 0.02 ) at 2 weeks and absorbable polylactic acid/citric acid ester base (p = 0.004) at 4 weeks. Electronic evaluation of the linear degree of fil l with one way ANOVA and Tukey's test found no significant difference (p > 0.05) among the experimental or the control groups. In addition, the Mann-Whitney U test indicated that removal forces required for den se polytetrafluoroethylene were significantly less than for expanded p olytetrafluoroethylene (p = 0.003). Conclusions. The use of dense poly tetrafluoroethylene as a membrane barrier deserves further investigati on as it allows osseous regeneration, it is easier to remove from heal ing soft tissues, and it is inexpensive. A study with larger sample si zes should be conducted.