Tb. Crump et al., INFLUENCE OF 3 MEMBRANE TYPES ON HEALING OF BONE DEFECTS, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 82(4), 1996, pp. 365-374
Citations number
44
Categorie Soggetti
Pathology,Surgery,"Dentistry,Oral Surgery & Medicine
Objectives. To determine and compare osseous regeneration associated w
ith three guided tissue regeneration membrane types (expanded polytetr
afluoroethylene, dense polytetrafluoroethylene, and an absorbable poly
lactic acid/citric acid ester base) and removal forces required for ex
panded and dense polytetrafluoroethylene membranes. Study design, Bila
teral osseous defects were created in 30 adult rat calvaria; one defec
t was covered with a lest membrane and the other received no membrane
(control). After 2 or 4 weeks, forces required for membrane removal fr
om the tissues were electronically determined, and the calvaria remove
d and decalcified. Sections through the defects were stained and evalu
ated electronically and microscopically. Data were analyzed statistica
lly. Results. Microscopic evaluation with Mann-Whitney U test revealed
that dense polytetrafluoroethylene was associated with significantly
greater bone formation than expanded polytetrafluoroethylene (p = 0.02
) at 2 weeks and absorbable polylactic acid/citric acid ester base (p
= 0.004) at 4 weeks. Electronic evaluation of the linear degree of fil
l with one way ANOVA and Tukey's test found no significant difference
(p > 0.05) among the experimental or the control groups. In addition,
the Mann-Whitney U test indicated that removal forces required for den
se polytetrafluoroethylene were significantly less than for expanded p
olytetrafluoroethylene (p = 0.003). Conclusions. The use of dense poly
tetrafluoroethylene as a membrane barrier deserves further investigati
on as it allows osseous regeneration, it is easier to remove from heal
ing soft tissues, and it is inexpensive. A study with larger sample si
zes should be conducted.