L. Lomuzio et al., ODONTOGENIC MYXOMA OF THE JAWS - A CLINICAL, RADIOLOGIC, IMMUNOHISTOCHEMICAL, AND ULTRASTRUCTURAL-STUDY, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 82(4), 1996, pp. 426-433
Citations number
24
Categorie Soggetti
Pathology,Surgery,"Dentistry,Oral Surgery & Medicine
Ten cases of odontogenic myxoma were evaluated radiologically, histolo
gically, and histochemically. Ultrastructural examination was performe
d in five cases. Stellate cells with branching processes were seen in
an abundant acid mucopolysaccharide background. Occasionally macrophag
es were found in the tumors. In two cases islands of inactive odontoge
nic epithelium were identified. The ultrastructural features suggest t
hat many lesional cells are very similar to a myofibroblast. With the
avidin-biotin complex immunohistochemical technique, the lesions were
rested with antibodies to S-100 protein, neuron-specific enolase, neur
ofilaments, glial fibrillary acid protein, keratin, desmin, muscle-spe
cific actin, and vimentin. All the lesions were found to be positive f
or vimentin and muscle-specific actin, and negative for the rest. The
results of our study seem to confirm the muscle-specific actin-positiv
ity of odontogenic myxomas as previously reported.