Cm. Goods et al., COMPARISON OF ASPIRIN ALONE VERSUS ASPIRIN PLUS TICLOPIDINE AFTER CORONARY-ARTERY STENTING, The American journal of cardiology, 78(9), 1996, pp. 1042-1044
This prospective nonrandomized study was performed comparing aspirin a
lone (n = 46) versus aspirin and ticlopidine (n = 338) following nativ
e coronary artery stenting. There were significantly more stent thromb
osis events in the aspirin-only group than in the aspirin and ticlopid
ine group (6.5% vs 0.9%, p = 0.02) and significantly more Q-wave myoca
rdial infarctions and cardiac-related deaths in the aspirin-only group
than in the aspirin and ticlopidine group (6.5% vs 0% p = 0.002 and 4
.4% vs 0.3%, p = 0.02, respectively).