Necrotizing acute pancreatitis is defined as necrosis of the adipose t
issue, interstitial tissue and glandular tissue associated with areas
of hemorrhage. Several causes are known predominantly biliary lithiasi
s and alcoholism. Severe consequences due to the release of pancreatic
enzymes include activation of inflammation mediators which can lead t
o multiple organ failure. Although no therapy has been proven to be ef
fective, progress in intensive care has helped reduce mortality. Rapid
diagnosis and evaluation of the severity of illness with specific or
general scores (Apache II score) are the keys to rapid management usin
g therapies adapted to the degree of organ failure. Indication for sur
gery must be established in coordination with surgeons and depends bot
h on the clinical course and computed tomography score.