Patients with delirium, dementia, depression, and schizophrenia were a
dministered a newly developed rest designed to identify delirium in an
intensive care unit (ICU) setting. Two alternate forms of the Cogniti
ve Test for Delirium (CTD) were highly correlated. The delirium patien
ts performed least well, and an optimal cutoff score derived from rela
tive-operating characteristic analysis resulted in a sensitivity of 10
0% and a specificity of 95%. In a follow-up study, the Mini-Mental Sta
te Exam could not be administered to 42% of the ICU patients who compl
eted the CTD. Early identification of delirium with the CTD may lead t
o timely treatment of specific etiologic conditions and a reduction in
mortality and morbidity.