Objective: The authors examined the association of cognitive impairmen
t with posttraumatic stress disorder (PTSD) and other psychiatric diag
noses known to affect cognitive functioning. Method: The results of st
andardized neuropsychological tests were compared in four groups of Vi
etnam veterans: veterans with both a lifetime history of PTSD and a cu
rrent diagnosis of depression, anxiety, or substance abuse; veterans w
ith only a PTSD diagnosis; veterans with only a current diagnosis of d
epression, anxiety, or substance abuse; and veterans with none of thes
e diagnoses. Results: Veterans with both PTSD and concurrent diagnoses
exhibited more impairment in cognitive functioning than did veterans
without these diagnoses. Conclusions: Cognitive deficits seen among pe
rsons diagnosed with PTSD may be associated with their concomitant dia
gnoses.